Dr. Dan Kuebler

Dr. Dan Kuebler

Professor of Biology

Dean of the School of Natural & Applied Sciences

DKuebler@franciscan.edu
(740) 284-5268

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  • University of California, Berkeley Berkeley, CA
    Ph.D. in Molecular and Cell Biology.
  • Catholic University of America, Washington, D.C.
    M.S. in Molecular Biology.
  • Catholic University of America, Washington, D.C.
    B.A. in English.
  • Dean, School of Natural and Applied Sciences: August 2018-present, Franciscan University of Steubenville
  • Chief Scientific Officer: Dec 2016-present, Franciscan Regenerative
  • SCIO Visiting Scholar in Science and Religion: Summer 2015 and 2016, Wycliffe Hall, Oxford, England
  • Regenerative Medicine Consultant: May 2015-present, Human Regenerative Technologies
  • Co-Director, Franciscan Institute of Science and Health: August 2013-present, Franciscan University of Steubenville
  • Professor of Biology: August 2001-present, Franciscan University of Steubenville
  • Co-Coordinator, Science and Faith Speaker Series: August 2012-present, Franciscan University of Steubenville
  • Legislative Assistant: April 2001 –August 2001, Rep. Ralph Regula (R), Washington, DC
  • Policy Analyst: August 2000 –April 2001, National Institute for Occupational Safety and Health, Washington, DC
  • Postdoctoral Researcher: January 2000 –July 2000, University of California, Berkeley

Regenerative Medicene Research

Knee osteoarthritis a common, debilitating condition that is estimated to affect nearly 27 million adults in the United States. Given the nature of this condition, regenerative medicine options hold much promise for treatment. Two common treatment options are fat tissue injections, which represent an abundant source of adult stem cells, and platelet-rich plasma injections. To further the development of such treatments, undergraduate students have been pursing a number of projects. The first involves analyzing and developing new methods to isolate high yields of healthy stem cells from adipose tissue. The second involves determining the effects that activated platelets and other biologics have on gene expression, protein secretion and cell division/growth of adipose-derived stem cells. Finally, we are pursuing animal models of osteoarthritis to test the efficacy of different combinations of these biologics to treat the disorder.

Read more about this research.

Research with Seizure Disorders

Millions of people in the US suffer from epilepsy, a heterogeneous collection of disorders that all involve spontaneous recurrent seizures that have no known trigger. Unfortunately, the etiology of epilepsy is poorly understood particularly given the diverse categories of genes that have been implicated in this disease. In order to understand the underlying cause of seizure disorders such as epilepsy, we study a family of seizure susceptible Drosophila mutants that are known as the Bang-sensitive (BS) paralytic mutants. Uncovering the underlying causative defect in these mutants represents the major line of investigation in our lab. Recently, we have demonstrated that metabolic alterations can have profound effects on seizure susceptibility in the BS mutants. Specifically, we have found that mutations and drugs that increase metabolism can reduce seizure intensity and duration. Undergraduate students, many of whom have presented at national meetings or have been authors on scientific publications, have performed all of this work. Currently we are examining the effect dietary changes have on seizure susceptibility as well as how the expression of metabolic genes is altered by various diets and pharmacological treatments. We hope that a better understanding of the link between metabolism and seizure susceptibility will shed light on the physiological defect(s) underlying seizure disorders in general.

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Select Publications
  • Kuebler, D.(2018) Genetic modification of embryos: The truth behind the research. Catholic World Report, Mar 21st.
  • Kuebler, D. (2016) IVF, designer babies, and commodifying human life. Public Discourse, Apr 7th.
  • Kuebler, D. (2014) Academic freedom, religious institutions and the state. Public Discourse, Nov 3rd.
  • Kuebler, D. (2014) Catholic universities conduct research on rare diseases. Crisis Magazine, Sept 5th.
  • Kuebler, D. (2014) Sugar and spice and……sex-selective abortions? Public Discourse, Jan 9th.
  • Kuebler, D. (2013) Americans and the clone-and kill mentality. National Catholic Register, Nov 23rd.
  • Kuebler, D. (2013) Survey says: Women are for life. Public Discourse, Oct 30th.

Full List

  • Kuebler, D. (2013) Memo to Lady Gaga: “Born this way” doesn’t mean act this way. Public Discourse, Apr 10th.
  • Kuebler, D. (2012) Failing grade in social doctrine. National Catholic Register, Sept 4, Vol 88:21.
  • Kuebler, D. (2012) Obama overreaches on HHS mandate. National Catholic Register, Feb 24, Vol 88:5.
  • Kuebler, D. (2012).The reality of research. National Catholic Register, Jan 4, Vol 88:2.
  • Kuebler, D. (2012) Franciscan, Ave Maria, and Obamacare.,Public Discourse June 13th.
  • Kuebler, D. (2011) The case against pro-life physicians: Bias begins at medical school. National Catholic Register, Sept 13-26, Vol 87:18.
  • Kuebler D. “Gut-Check Time for Catholic Coaches,” National Catholic Register, Sept 12-25, 2010: Vol 86:19.
  • Kuebler D. “When Reform Deforms,” National Catholic Register, Jan 2-8, 2010: Vol 86:1.
  • Kuebler D. “The Mess Money Made,” National Catholic Register, May 10-16, 2009: Vol 85:19.
  • Kuebler D. “Catholic Pro-Life Politics,” National Catholic Register, Jan 18-24, 2009: Vol 85:3.
  • Kuebler D. “Battle Over a Single Word,” National Catholic Register, June 29-July 5, 2008: Vol
    84:24.
  • Kuebler D. “Stem Cells Simply,” National Catholic Register, Dec 9-15, 2007: Vol 83:50.
  • Kuebler D. “When Death is Part of Life,” National Catholic Register, Mar 11-17, 2007: Vol 83:12.
  • Kuebler D. “What Makes Marriage Special,” National Catholic Register, Oct 22- Oct 28, 2006: Vol 82:43.
  • Kuebler D. “For Girls Only: The Steroids Double Standard,” National Catholic Register, Nov 27-Dec 3, 2005: Vol 81:47.
  • Kuebler D. “America and the Academy,” National Catholic Register, July 3-July 9, 2005: Vol 81:27.
  • Kuebler D. “John Paul Brought Us Face to Face With Christ,” National Catholic Register, Apr 17-Apr 23, 2005: Vol 81:16.
  • Kuebler D. “California’s Bad Move,” National Catholic Register, Jan 16-Jan 22, 2005: Vol 81:3.
  • Kuebler D. “Our Soldiers”, National Catholic Register, May 23-29, 2004: Vol 80:21.
  • Kuebler D. “Where Catholic Universities Can Lead the Way,” National Catholic Register, Feb 1-7, 2004: Vol 80:5.
Department Faculty